Artificial Lung Surfactant

Artificial Lung Surfactant

Testonic® Artificial Lung Surfactant is an ISO 18562-3 compliant low surface tension fluid for VOC emission and respiratory interface simulation studies.

  • Ready-to-use formulation
  • Suitable for analytical laboratory use
  • Reproducible and reliable results
  • Formulation simulating biological environment
  • Provides standards-compliant test medium
  • Suitable for material stability and compatibility testing
  • Mimics physiological pH and ionic balance
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Product Code: 406
Barcode: 8680131854066
Last update: 29 Kasım 2025 , Cumartesi

Simulated Pulmonary Surfactant for Respiratory Device Testing – ISO 18562-3 Compliant

Testonic® Artificial Lung Surfactant is a lipid-protein based simulation fluid formulated for the evaluation of ventilators, nebulizers, endotracheal tubes, and other respiratory devices in accordance with ISO 18562-3. Designed to mimic the physicochemical behavior of natural pulmonary surfactant in alveoli, it provides a reliable medium for VOC (volatile organic compound) emission testing, surface interaction analysis, and biocompatibility studies of breathing gas pathways.


Application Areas

  • VOC emission testing for respiratory devices (ISO 18562-3)

  • Surface compatibility testing of ventilators, oxygen masks, and nebulizers

  • Alveolar surfactant simulation for in vitro studies

  • Evaluation of lipid–protein interaction with breathing circuit components

  • Biocompatibility assessments of respiratory product surfaces


Formulation Features

Property

 

pH: 6.8 ± 0.2 (HEPES-buffered)

 

Surface tension: ≤ 30 mN/m (mimics natural pulmonary levels)

 

Appearance: Slightly viscous, opalescent fluid

 

Composition: Phosphatidylcholine, palmitic acid, cholesterol, BSA

 

Emulsion stability: Enhanced with Tween 80 and ethanol

 

Biological relevance: Simulates natural lung surfactant film dynamics

 

Product Features

  • Accurately replicates the biophysical behavior of alveolar surfactant

  • Provides a stable, VOC-compatible test medium for ISO 18562-3 studies

  • Non-cytotoxic and filter-sterilizable

  • Suitable for both quality control and R&D testing of respiratory devices


Usage Instructions & Storage Conditions

  • Shake well before use to ensure uniform dispersion

  • Adjust pH if needed using 1 M NaOH or HCl

  • Do not freeze

  • Shelf life: 30 days with preservative; 7 days preservative-free


Why Choose Testonic® Artificial Lung Surfactant?

  • Fully compliant with ISO 18562-3 for respiratory gas pathway testing

  • Reproduces low surface tension and surfactant lipid dynamics of alveoli

  • Offers high reproducibility for VOC emission, biocompatibility, and interface studies

Technical Documents

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